Use of the J&J shot has been weak in high-income international locations, harm by experiences of uncommon, doubtlessly lethal blood clots, manufacturing points, together with an unintended mix-up of components by a contract producer, and considerations about efficacy
The US well being regulator stated on Thursday, May 5, it was limiting the usage of Johnson & Johnson’s JNJ.N COVID-19 vaccine for adults because of the threat of a uncommon blood clotting syndrome, the most recent setback to the shot that has been eclipsed by rivals.
The J&J shot, which acquired US clearance in February 2021 for adults, may be administered in circumstances the place approved or accepted COVID-19 vaccines should not accessible or if a person is much less eager on utilizing the opposite two photographs, the Food and Drug Administration stated.
J&J is without doubt one of the three vaccines in use within the United States. The different two are from Moderna MRNA.O and Pfizer PFE.N.
The vaccine maker stated it has up to date the US COVID-19 vaccine truth sheet to warn in regards to the threat of thrombosis with thrombocytopenia syndrome (TTS), a uncommon however doubtlessly life-threatening situation.
Use of the J&J shot has been weak in high-income international locations, harm by experiences of uncommon, doubtlessly lethal blood clots, manufacturing points, together with an unintended mix-up of components by a contract producer, and considerations about efficacy.
The drugmaker final month rescinded its forecast for COVID-19 vaccine gross sales, citing a glut of provide. Read full story
Cases of TTS, which entails blood clots accompanied by a low stage of platelets, have beforehand been reported in recipients of the J&J vaccine.
The FDA in January amended the very fact sheet for the J&J vaccine to incorporate the danger of immune thrombocytopenia, months after the European Union’s medicine regulator took comparable motion.
The FDA on Thursday stated the danger of TTS warranted limiting the usage of the single-dose shot after it carried out investigation of reported circumstances.
The US Centers for Disease Control and Prevention in December had really helpful that Americans select to obtain mRNA photographs from Pfizer and Moderna over J&J’s vaccine because of the uncommon circumstances of blood clotting.
Around 18.7 million Americans have acquired a J&J COVID-19 shot in contrast with 217.5 million individuals who acquired the Moderna vaccine and 340.6 million individuals who acquired Pfizer’s shot, in response to CDC. – Rappler.com